Evaluation of Candida auris Colonization using Clinical Skin Swabs: A Single-Center Study in Isfahan, Iran
عنوان مقاله: Evaluation of Candida auris Colonization using Clinical Skin Swabs: A Single-Center Study in Isfahan, Iran
شناسه ملی مقاله: JR_IJHLS-8-3_008
منتشر شده در در سال 1401
شناسه ملی مقاله: JR_IJHLS-8-3_008
منتشر شده در در سال 1401
مشخصات نویسندگان مقاله:
Fatemeh Safari - Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Mahboobeh Madani - Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Hossein Mirhendi - Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran- Research Core Facilities Laboratory, Mycology Reference Laboratory, Isfahan University of Medical Sciences, Isfahan, Iran
Majid Kheirollahi - Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
خلاصه مقاله:
Fatemeh Safari - Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Mahboobeh Madani - Department of Microbiology, Falavarjan Branch, Islamic Azad University, Isfahan, Iran
Hossein Mirhendi - Department of Parasitology and Mycology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran- Research Core Facilities Laboratory, Mycology Reference Laboratory, Isfahan University of Medical Sciences, Isfahan, Iran
Majid Kheirollahi - Department of Genetics and Molecular Biology, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
The multidrug-resistant fungal pathogen Candida auris has been associated with healthcare.We need to address COVID-۱۹ pandemic
as well as the ongoing global fungal epidemic caused by C. auris, a multi-drug-resistant fungus spreading rapidly throughout the
world. This study was conducted on patients admitted to an ICU in Isfahan, Iran, from November ۲۰۲۰ to February ۲۰۲۱ to determine
the spectrum of C. auris colonization in immunocompromised patients hospitalized in an intensive care unit (ICU). Therefore, clinical
swabs were collected from ۳۲ immunocompromised patients for C. auris detection upon ICU admission after ۷ to ۱۴ days. A rich
culturemediumwas used to evaluate C. auris growth at a higher temperature (۴۰°C) and salinity (۱۰% wt/vol) in Sabouraud dextrose
agar, which can be used in combination with a C. auris-specific polymerase chain reaction method. C. auris was not isolated in the
clinical samples of patients. The most common colonizer was Candida albicans, followed by C. glabrata, C. parapsilosis, and C. tropicalis.
Candida glabrata was the only species with noticeable growth in the Salt SDA, with D-Mannitol as a carbon source. Currently, C.
auris is not a common cause of systemic or superficial fungal infections in Iran. The screening of patients admitted to the ICU for C.
auris could aid in the identification of colonized patients and could simplify the application of infection control measures.
کلمات کلیدی: Candida auris, Colonization, Culture, C. auris-specific PCR
صفحه اختصاصی مقاله و دریافت فایل کامل: https://civilica.com/doc/1700710/