The Effect of Chlorella Vulgaris vs. Artichoke on Patients with Non-alcoholic Fatty Liver Disease (NAFLD): A Randomized Clinical Trial

سال انتشار: 1394
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 245

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شناسه ملی سند علمی:

JR_ZUMS-23-100_004

تاریخ نمایه سازی: 11 اردیبهشت 1400

چکیده مقاله:

Background and Objective: Non-alcoholic fatty liver disease has been identified as a major health -related problem.There is no proven therapy for NAFLD. However, a number of possible treatments have been proposed and studied. The aim of this study was to evaluate the therapeutic effects of both Chlorella Vulgaris and Artichoke leaf extracts on NAFLD. Materials and Methods: In this clinical trial study, ۹۰ patients with NAFLD participated and randomly allocated to three groups. After initial examination, lipids and liver enzymes were measured. The groups received Metformin, Chlorella supplements and Artichoke. After the therapeutic period, liver enzymes were measured again. All collected data were analyzed using SPSS software and independent T-Test, Mann-Whitney and Chi-Square tests. Results: At baseline, mean age, systolic and diastolic blood pressure, BMI, ALT, AST, HDL, LDL, TG, CHOL and FBS showed no significant difference in three groups. But, after the completion of the treatment, serum ALT, AST, systolic and diastolic blood pressure and BMI significantly decreased in all three groups. Conclusion: Our study showed the beneficial effects of Artichoke and Chlorella vulgaris in patients with NAFLD. We suggest future studies be performed with larger sample sizes for precise evaluation of the effects of Artichoke and Chlorella vulgaris on NAFLD.

نویسندگان

بهمن طالبی پور

Dept.of Internal Medicine, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

مریم جامه شورانی

Zanjan Metabolic Disease Research Center, Zanjan University of Medical Sciences, Zanjan, Iran

رضا سلمانی

Dept.of Internal Medicine, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

حسین چیتی

Dept.of Internal Medicine, Faculty of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran

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  • References 1- MK Oh, Winn F. Diagnosis and treatment of ...
  • Adams LA, Angulo P. "Treatment of non-alcoholic fatty liver disease". ...
  • Clark JM, Diehl AM. "Nonalcoholic fatty liver disease: an underrecognized ...
  • Adams LA, Waters R, Knuiman M, et al. NAFLD as ...
  • Huang MA, Greenson JK, Chao C, et al. One-year intense ...
  • Bugiaresi E, Gentilcore E, Manini R, et al. A randomized ...
  • Duseja A, Das A, Dhiman R, et al. "Metformin is ...
  • Belfort R, Harrison SA, Brown K, et al. "A placebo-controlled ...
  • Sanyal AJ, Chalasani N, Kowdley KV, et al. "Pioglitazone, vitamin ...
  • Kok N, Roberfroid M, Robert A, Delzenne NM. Involvement of ...
  • Daubioul CA, Horsman Y, Lambert P, Danse E, Delzenne NM. ...
  • Wider B, Pittler MH, Thompson-Coon J, Ernst E. Artichoke leaf ...
  • Bundy R, Waker AF, Middoton RW, et al. Artichoke leaf ...
  • Mizoguchi T, Takeharo I, Masuzawa T, et al. Nutricogenomic studies ...
  • Suzuki A, Lindor K, St Saver J, et al, Effect ...
  • LC Wu, JA Annie Ho, et al. Antioxidant and antiproliferative ...
  • Panahi Y. (2010) Abstracts of papers, third international Tehran hepatitis ...
  • Pittler MH, Thompson Coon J, Ernst E. Artichoke leaf extract ...
  • Capasso F, Gaginella TS, Grandolini G, Izzo AA. Phytotherapy: A ...
  • Artner-Dworzak E, Mayr a, Mueller B, Maly K, Grunicke H. ...
  • Sano T, Tanaka Y. (1987) Effect of dry, powdered chlorella ...
  • Chemg JY, Shih MF. (2005) preventing dyslipidemia by chlorella pyrenidosa ...
  • نمایش کامل مراجع