scaffolds composed of polyurethane (PU)/ poly(glycerol sebacate)(PGS) : The promising candidate for soft tissue engineering

There is a continuing need for organ regeneration, repair, and transplantation because of a wide range of infectious, congenital, and acute disorders. Tissue engineering (TE) is a highly effective method for repairing damaged tissues that goes beyond traditional medical approaches. It involves the integration of scaffolds, growth factors, and cells. The use of scaffolds in tissue engineering is crucial. Scaffolding is mostly made of biodegradable polymers that provide good processing flexibility. Synthetic biodegradable polymers with a well defined structure are widely used in tissue engineering and do not cause immunological problems that are commonly associated with naturally occurring polymers. The synthetic biodegradable polymers, including polyurethane(PU) and poly(glycerol sebacate)(PGS), that are often used in tissue engineering are outlined in the section that follows. In addition, this work analyses composite and nanocomposite scaffolds and looks at scaffold designs that mimic the micro and nano properties of the extracellular matrix (ECM).

کلیدواژه ها:

scaffolds ، tissue engineering ، synthetic biodegradable polymers ، polyurethane ، poly(glycerol sebacate)